Toxicological Profile for 1,2-Diphenylhydrazine
Title: Toxicological Profile for 1,2-Diphenylhydrazine
Subject of Planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.
Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.
Type of Dissemination: ISI
Timing of Review (including deferrals): May 2018
Type of Review (panel, individual or alternative procedure): Individual
Opportunities for the Public to Comment (how and when): A draft of this profile was made available for public comment June 2019
Peer Reviewers Provided with Public Comments before the Review: No
Anticipated Number of Reviewers: 3
Primary Disciplines or Expertise: toxicology, environmental health, chemistry
Reviewers Selected by (agency or designated outside organization): CDC/ATSDR
Public Nominations Requested for Reviewers: No
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Professor |
| Organizational Affiliation(s) | Laboratório de Ecotoxicologia e Genotoxicidade LAEG Faculdade de Tecnologia UNICAMP, Brazil |
| Areas of Expertise, Discipline, Relevant Experiences | Expertise / Discipline: environmental and regulatory toxicology, mutagenesis, ecotoxicology, toxicology of dyes and pesticides in water Experience: Dr. Umbuzeiro graduated in Biology in the State University of Campinas- UNICAMP (1979), master’s and in Genetics and Molecular Biology from UNICAMP (1985) and Ph.D. in Genetics and Molecular Biology from UNICAMP (1990). She has been a visiting Professor at NIEHS and USEPA and a full professor at State University of Campinas – Faculty of Technology -UNICAMP. She worked for 22 years for the Environmental Protection Agency of the São Paulo State of Brazil (CETESB); was president of the Mutagen Society Member of the Editorial Board of Environmental Molecular Mutagenesis journal; and is an expert and a member of the UNESCO-International Initiative on water quality Experts Advisory Group. |
| Recommended by Scientific/Professional Society or General Public | No |
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Toxicologist |
| Organizational Affiliation(s) | General Toxicology and Cancer Group, NIH |
| Areas of Expertise, Discipline, Relevant Experiences | Expertise / Discipline: toxicology, molecular biology, mixtures Experience: Dr Rider designs and evaluates results from toxicological studies of chemicals selected for investigation by the NTP. She is particularly interested in developing methods for assessing mixture toxicity based on data from individual chemicals. Dr. Rider received her B.S. from Tulane University, New Orleans, LA in Environmental Studies and Biology and her Ph.D. from North Carolina State University, Raleigh, NC in Environmental Toxicology. She completed post-doctoral training in the Reproductive Toxicology Branch of the National Health and Environmental Effects Research Laboratory, U. S. Environmental Protection Agency and the Nicholas School of the Environment at Duke University. |
| Recommended by Scientific/Professional Society or General Public | No |
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Associate Professor of Chemistry |
| Organizational Affiliation(s) | Department of Chemistry University of Pennsylvania |
| Areas of Expertise, Discipline, Relevant Experiences | Expertise / Discipline: inorganic and materials chemistry, molecular complexes Experience: inert atmosphere/Schlenk line synthesis of inorganic and organometallic complexes; use of x-ray crystallography, NMR, FTIR, and UV-Visible absorption spectroscopies, electrochemistry and magnetic susceptibility studies; chemistries and electronic structure effects of the lanthanides, uranium and main group elements. Dr. Schelter received his B.S. degree from Michigan Technological University (1999), Ph.D. from Texas A&M University, followed by postdoctoral fellowships at Los Alamos National Laboratory. In 2009, he became Assistant Professor of Chemistry at the University of Pennsylvania, and Associate Professor of Chemistry in 2015. He received the ACS Harry Gray Award for Creative Work in Inorganic Chemistry by a Young Investigator (2016); is on the Editorial Advisory Board Member of Inorganic Chemistry (2016-2018); ACS Division of Inorganic Chemistry, Chair Elect (2016); fellow of the Royal Society of Chemistry (2017) and U.S. Environmental Protection Agency Green Chemistry Challenge Award Recipient (2017). |
| Recommended by Scientific/Professional Society or General Public | No |
Charge to Peer Reviewers: Charge to Peer Reviewers 1,2-diphenylhydrazine
Peer Reviewers’ Comments and CDC/ATSDR’s Response to Reviewers’ Comments: DISPOSITION OF PEER REVIEW COMMENTS FOR TOXICOLOGICAL PROFILE FOR 1,2-DIPHENYLHYDRAZINE [PDF – 299 KB]
The ISI/HISA Dissemination Itself: https://wwwn.cdc.gov/TSP/ToxProfiles/ToxProfiles.aspx?id=952&tid=198