Toxicological Profile for Glyphosates
Title: Toxicological Profile for Glyphosates
Subject of Planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.
Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.
Type of Dissemination: ISI
Timing of Review (including deferrals): August 2017
Type of Review (panel, individual or alternative procedure): Individual
Opportunities for the Public to Comment (how and when):A draft of this profile will be made available for public comment in 2018
Peer Reviewers Provided with Public Comments before the Review: No
Anticipated Number of Reviewers: 3
Primary Disciplines or Expertise: toxicology, environmental health, chemistry
Reviewers Selected by (agency or designated outside organization): CDC/ATSDR
Public Nominations Requested for Reviewers: No
| Academic and Professional Credentials | PhD, MPH |
|---|---|
| Current Position Title | Associate Professor |
| Organizational Affiliation(s) | Environmental and Occupational Health Drexel University Dornsife School of Public Health |
| Areas of Expertise, Discipline, Relevant Experiences | Expertise / Discipline: study of occupational and environmental exposures to chemicals and radiation as risk factors for cancer, autoimmune diseases, and intermediate biologic effects. Other research includes spatial analysis (GIS), built environment, urban health, pesticides, risk assessment, drinking water, etc.
Experience: current faculty at, former faculty at the University of Washington and Fred Hutchinson Cancer Research Center in Seattle, WA. Research focused on environmental risk factors for cancers, including workplace exposures (pesticides, solvents), persistent organic pollutants (PCBs, dioxins), and point sources of pollution (industrial facilities, traffic). Dr de Roos had numerous NIH and other grants; and is the primary instructor for “Risk Analysis for Environmental Health,” at Drexel. She has served on several expert committees in recent years, including those reviewing NIEHS’s Report on Carcinogens for formaldehyde, and EPA’s draft health risk assessment documents for trichloroethylene (TCE) and consumer use of paint stripper products. |
| Recommended by Scientific/Professional Society or General Public |
No |
| Academic and Professional Credentials | DVM, MSc, PhD, |
|---|---|
| Current Position Title | Professor |
| Organizational Affiliation(s) | Department of Pharmacy, State University of Centro-Oeste UNICENTRO |
| Areas of Expertise, Discipline, Relevant Experiences | Dr. Romano has expertise in veterinary medicine, animal reproduction, human physiology, and pharmacology. Dr. Romano has numerous peer reviewed publications, and research grants. He is a member of the Bioethics Committee of the ICB /USP (2008-2011); is responsible technique of Animal Experimentation Laboratory of the Health Sciences Sector (Unicentro) since 2015. He has experience in the areas of endocrine physiology and toxicology of reproduction. He was a Professor at the University of Franca, in the Educational Foundation of Guarapuava and PAE Program FMVZ-USP; and is an active member of the Brazilian Society of Physiology and the Latin American Thyroid Society. |
| Recommended by Scientific/Professional Society or General Public |
No |
| Academic and Professional Credentials | PhD, MS |
|---|---|
| Current Position Title | Professor of Cell Biology and Toxicologist; Department Chair |
| Organizational Affiliation(s) | Department of Molecular, Cell and Systems Biology University of California, Riverside |
| Areas of Expertise, Discipline, Relevant Experiences | Expertise / Discipline: mechanisms of toxicity and carcinogenesis of agricultural and environmental chemicals in humans and other mammalsExperience: mechanisms involved in the toxicity and carcinogenesis of environmental and agricultural chemicals; special emphasis on accurate estimation of adverse health effects associated with chemical exposure in human populations. Investigations are performed using a variety of chemical, biochemical and molecular approaches with isolated enzyme, cell culture and animal model systems. Current research studies the metabolism and chromosome-damaging effects of several cancer-causing agents, pesticides, fungicides and disinfectants; and tobacco smoke.
In addition, the Eastmond laboratory has an active research program in which molecular cytogenetic techniques are used to detect chromosomal alterations occurring in chemically exposed human populations. |
| Recommended by Scientific/Professional Society or General Public |
No |
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Professor of Family Medicine and Public Health Chief, Division of Behavioral Medicine Director, Center of Excellence for Research and Training in Integrative Health Director, Integrative Health and Mind-Body Biomarker Laboratory Co-Director, Translational Research Technologies Division, Clinical and Translational Research Institute |
| Organizational Affiliation(s) | University of California, San Diego 9500 Gilman Drive La Jolla, CA. 92093-0725 |
| Areas of Expertise, Discipline, Relevant Experiences | Psychoneuroimmunology, traditional medicine systems, whole systems medicine, behavioral medicine, integrative medicine |
| Recommended by Scientific/Professional Society or General Public |
No |
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Professor emeritus, Interdisciplinary Toxicology Program, Pharmaceutical & Biomedical Sciences, College of Pharmacy |
| Organizational Affiliation(s) | University of Georgia, Athens, GA |
| Areas of Expertise, Discipline, Relevant Experiences | Toxicology; Pharmacokinetics including PBPK modeling |
| Recommended by Scientific/Professional Society or General Public |
No |
Charge to Peer Reviewers DTEM Charge to Peer Reviewers
Additional elements to be added to the public posting as they become available
Draft for Public Comment Toxicological Profile for Glyphosate April 2019 pdf icon[PDF – 5 MB]
CDC/ATSDR’s Response to Reviewers’ Comments: