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Public Health Assessment
Fish and Shellfish Evaluation,
Isla de Vieques Bombing Range,
Vieques, Puerto Rico
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June 27, 2003
Prepared by:
Federal Facilities Assessment Branch
Division of Health Assessment and Consultation
Agency for Toxic Substances and Disease Registry
Appendix D Continued
| Location | Fish | Shellfish | ||||
|---|---|---|---|---|---|---|
| Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | |||
| Adult | Child | Adult | Child | |||
| 1 - North LIA | 0.13 | 0.0004 | 0.0009 | 0.03 | 0.0001 | 0.0002 |
| 2 - South LIA | 0.09 | 0.0003 | 0.0006 | 0.02 | 0.0001 | 0.0001 |
| 3 - Esperanza | 0.15 | 0.0005 | 0.0011 | 0.04 | 0.0001 | 0.0003 |
| 4 - Isabel Segunda | 0.09 | 0.0003 | 0.0006 | NS | NS | NS |
| 5 - Fish Market | 0.09 | 0.0003 | 0.0006 | 0.03 | 0.0001 | 0.0002 |
| 6 - West Vieques | 0.13 | 0.0004 | 0.0009 | 0.03 | 0.0001 | 0.0002 |
| All Locations | 0.12 | 0.0004 | 0.0009 | 0.03 | 0.0001 | 0.0002 |
Notes: Averages were calculated using detected values only.
Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT).
No adverse health effects were reported from exposure to 0.0013 mg/kg/day.
NS = not sampled
| Location | Fish | Shellfish | ||||
|---|---|---|---|---|---|---|
| Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | |||
| Adult | Child | Adult | Child | |||
| 1 - North LIA | 0.82 | 0.0027 | 0.0058 | 0.80 | 0.0026 | 0.0057 |
| 2 - South LIA | 1.05 | 0.0034 | 0.0074 | 0.80 | 0.0026 | 0.0057 |
| 3 - Esperanza | 1.03 | 0.0033 | 0.0073 | 0.85 | 0.0028 | 0.0060 |
| 4 - Isabel Segunda | 0.84 | 0.0027 | 0.0060 | NS | NS | NS |
| 5 - Fish Market | 1.15 | 0.0037 | 0.0082 | 0.74 | 0.0024 | 0.0052 |
| 6 - West Vieques | 0.93 | 0.0030 | 0.0066 | 0.79 | 0.0026 | 0.0056 |
| All Locations | 0.98 | 0.0032 | 0.0070 | 0.80 | 0.0026 | 0.0057 |
Notes: Averages were calculated using detected values only.
Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT).
No adverse health effects were reported from exposure to 0.015 mg/kg/day.
NS = not sampled
| Location | Shellfish | ||
|---|---|---|---|
| Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | ||
| Adult | Child | ||
| 1 - North LIA | 45.2 | 0.147 | 0.321 |
| 2 - South LIA | 44.1 | 0.143 | 0.313 |
| 3 - Esperanza | 11.2 | 0.036 | 0.079 |
| 4 - Isabel Segunda | NS | NS | NS |
| 5 - Fish Market | 18.3 | 0.059 | 0.130 |
| 6 - West Vieques | 8.0 | 0.026 | 0.057 |
| All Locations | 30.1 | 0.098 | 0.214 |
Notes: Averages were calculated using detected values only.
Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT).
Fish did not contain levels of zinc above health concern at any location.
Health effects were reported from exposure to 0.83 mg/kg/day.
NS = not sampled
| Metal | Maximum Detected Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | Oral Health Guideline (mg/kg/day) | Basis for Health Guideline | |
|---|---|---|---|---|---|
| Adult | Child | ||||
| Aluminum | 10.8 | 0.0350 | 0.0766 | 1.0 | chronic RfD |
| Arsenic | 21.4 | 0.0694* | 0.1518* | 0.0003 | chronic MRL/RfD |
| Barium | 0.19 | 0.0006 | 0.0013 | 0.07 | chronic RfD |
| Beryllium | 0.01 | 0.00003 | 0.00007 | 0.001 | chronic MRL |
| Chromium | 0.37 | 0.0012 | 0.0026 | 0.003 | chronic RfD (CrVI) |
| Cobalt | 0.09 | 0.0003 | 0.0006 | 0.02 | chronic RfD |
| Copper | 8.21 | 0.0266 | 0.0582* | 0.04 | chronic RfD |
| Iron | 6.51 | 0.0211 | 0.0462 | 0.3 | chronic RfD |
| Lead | 0.37 | 0.0012 | 0.0026 | NA | NA |
| Manganese | 2.02 | 0.0066 | 0.0143 | 0.14 | chronic RfD (food) |
| Mercury | 0.09 | 0.0003* | 0.0006* | 0.0001 | chronic RfD |
| Methylmercury | 0.018 | 0.00006 | 0.00013* | 0.0001 | chronic RfD |
| Nickel | 0.35 | 0.0011 | 0.0025 | 0.02 | chronic RfD |
| Silver | 0.11 | 0.0004 | 0.0008 | 0.005 | chronic RfD |
| Selenium | 1.94 | 0.0063* | 0.0138* | 0.005 | chronic MRL/RfD |
| Zinc | 21.0 | 0.0681 | 0.1490 | 0.3 | chronic MRL/RfD |
* Estimated exposure exceeds health guideline; however, an exposure dose that is higher than the MRL or RfD does not necessarily result in harmful health effects. These metals are further evaluated.
Notes: Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT).
NA = not available
| Metal | Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | |
|---|---|---|---|
| Adult | Child | ||
| Arsenic, inorganic | 5.64 | 0.0037 | 0.0080 |
| Lead | 0.21 | 0.0007 | 0.0015 |
| Mercury | 0.05 | 0.0002 | 0.0004 |
| Selenium | 1.12 | 0.0036 | 0.0079 |
| Estimated Daily Dose (mg/day) | |||
| Copper | 1.02 | 0.23 | 0.12 |
| Estimated Blood Lead Level (mg/dl) | |||
| Lead | 0.21 | 0.05 | 0.05 |
Notes: Averages were calculated using detected values only.
Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT). To calculate the exposure dose for inorganic arsenic the total arsenic concentration was used along with a conversion factor of 0.2 in the numerator.
Daily doses were calculated using the following formula: Dose = Conc. x IR.
The body metabolizes arsenic into a less harmful form at doses of 0.05 mg/kg/day.
Health effects were reported from exposure to arsenic at doses of 0.014 mg/kg/day.
Cancer effects were reported from exposures to arsenic at doses of 0.01-0.05 mg/kg/day.
No adverse health effects were reported from exposure to lead at doses of 0.57-27 mg/kg/day.
CDC's blood lead level of concern is 10 mg/dl.
No adverse health effects were reported from exposure to mercury at doses of 0.0013 mg/kg/day.
No adverse health effects were reported from exposure to selenium at doses of 0.015 mg/kg/day.
No adverse health effects were reported from exposure to copper at doses of 10 mg/day.
| Metal | Maximum Detected Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | Oral Health Guideline (mg/kg/day) | Basis for Health Guideline | |
|---|---|---|---|---|---|
| Adult | Child | ||||
| Arsenic | 29.3 | 0.0190* | 0.0416* | 0.0003 | chronic MRL/RfD |
| Chromium | 0.08 | 0.0003 | 0.0006 | 0.003 | chronic RfD (CrVI) |
| Copper | 0.36 | 0.0012 | 0.0026 | 0.04 | chronic RfD |
| Selenium | 2.5 | 0.0080* | 0.0176* | 0.005 | chronic MRL/RfD |
* Estimated exposure exceeds health guideline; however, an exposure dose that is higher than the MRL or RfD does not necessarily result in harmful health effects. These metals are further evaluated.
Notes: Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT).To calculate the exposure dose for inorganic arsenic the total arsenic concentration was used along with a conversion factor of 0.2 in the numerator.
The body metabolizes arsenic into a less harmful form at doses of 0.05 mg/kg/day.
Health effects were reported from exposure to arsenic at doses of 0.014 mg/kg/day.
Cancer effects were reported from exposures to arsenic at doses of 0.01-0.05 mg/kg/day.
Health effects were reported from exposure to selenium at doses of 0.023 mg/kg/day.
| Metal | Maximum Detected Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | Oral Health Guideline (mg/kg/day) | Basis for Health Guideline | |
|---|---|---|---|---|---|
| Adult | Child | ||||
| Arsenic | 7.2 | 0.0047* | 0.0102* | 0.0003 | chronic MRL/RfD |
| Cadmium | 0.028 | 0.00009 | 0.00019 | 0.001 | chronic RfD (food) |
| Lead | 0.2 | 0.0006 | 0.0014 | NA | NA |
| Mercury | 0.38 | 0.0012* | 0.0027* | 0.0001 | chronic RfD |
| Selenium | 1.3 | 0.0042 | 0.0092* | 0.005 | chronic MRL/RfD |
| Zinc | 9.1 | 0.0295 | 0.0646 | 0.3 | chronic MRL/RfD |
* Estimated exposure exceeds health guideline; however, an exposure dose that is higher than the MRL or RfD does not necessarily result in harmful health effects. These metals are further evaluated.
Source: Caro et al. 2000
Notes: Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT).
NA = not available
| Metal | Average Concentration (ppm) | Estimated Exposure Dose (mg/kg/day) | |
|---|---|---|---|
| Adult | Child | ||
| Arsenic, inorganic | 1.2 | 0.0008 | 0.0017 |
| Lead | 0.2 | 0.0006 | 0.0014 |
| Mercury | 0.024 | 0.0001 | 0.0002 |
| Selenium | 0.6 | 0.0019 | 0.0043 |
| Estimated Blood Lead Level (mg/dl) | |||
| Lead | 0.2 | 0.05 | 0.05 |
Source: Caro et al. 2000
Notes: Averages were calculated using detected values only.
Exposure doses were calculated using 365 days/year for EF in the formula described in the Deriving exposure doses section of this appendix: (Conc. x IR x EF x ED) / (BW x AT). To calculate the exposure dose for inorganic arsenic the total arsenic concentration was used along with a conversion factor of 0.2 in the numerator.
The body metabolizes arsenic into a less harmful form at doses of 0.05 mg/kg/day.
Health effects were reported from exposure to arsenic at doses of 0.014 mg/kg/day.
Cancer effects were reported from exposures to arsenic at doses of 0.01-0.05 mg/kg/day.
No adverse health effects were reported from exposure to lead at doses of 0.57-27 mg/kg/day.
CDC's blood lead level of concern is 10 mg/dl.
No adverse health effects were reported from exposure to mercury at doses of 0.0013 mg/kg/day.
No adverse health effects were reported from exposure to selenium at doses of 0.015 mg/kg/day.
