Trichlorobenzenes

Toxicological Profile

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of trichlorobenzenes.

Details

Title: Toxicological Profile for Trichlorobenzenes

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): August 2010

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile was made available on October 17, 2010. The draft was available for a 90-day public comment period.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3 or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Charge to Peer Reviewers: DTEM Charge to Peer Reviewers

Reviewers

Academic and Professional Credentials
Ph.D.
Current Position Title
Professor, Biostatistics
Organizational Affiliation(s)
College of Public Health, University of Arkansas for Medical Sciences
American Statistical Association
Academy of Toxicological Sciences
Areas of Expertise, Discipline, Relevant
Experiences
Dr. Kodell has knowledge of trichlorobenzenes’:

  • Physical and chemical properties
  • Toxicokinetics
  • Key health end points
  • Mechanisms of action
  • Human and animal exposure
  • Quantification of risk to humans.
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
Ph.D.
Current Position Title
President, MoBull Consulting, Richland Washington
Organizational Affiliation(s)
MoBull Consulting
Areas of Expertise, Discipline, Relevant
Experiences
Dr. Bull has knowledge of trichlorobenzenes’:

  • Physical and chemical properties
  • Toxicokinetics
  • Key health end points
  • Mechanisms of action
  • Human and animal exposure
  • Quantification of risk to humans.
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
Ph.D.
Current Position Title
Professor and Chair, Department of Environmental Health, School of Public Health, Indiana University, Bloomington
Organizational Affiliation(s)
Indiana University
IU Simon Cancer Center
Areas of Expertise, Discipline, Relevant
Experiences
Dr. Klaunig has knowledge of trichlorobenzenes’:

  • Physical and chemical properties
  • Toxicokinetics
  • Key health end points
  • Mechanisms of action
  • Human and animal exposure
  • Quantification of risk to humans.
Recommended by Scientific/Professional
Society or General Public
No

Resources

Peer Reviewers’ Comments: Trichlorobenzene Summary Report
Download
Download
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for Trichlorobenzene
Download
Download
The ISI/HISA Dissemination Itself
Print
Content Source:
Agency for Toxic Substances and Disease Registry