Toluene Diisocyanate

Toxicological Profile

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of toluene diisocyanate.

Details

Title: Toxicological Profile for Toluene Diisocyanate

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2014

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile will be made available for public comment in 2015.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3 or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials
PhD
Current Position Title
Principal Consultant
Organizational Affiliation(s)
Systox, Ltd.
84 Hazelwood Rd
Wilmslow, Cheshire, SK92QA
United Kingdom
Areas of Expertise, Discipline, Relevant Experiences
Areas of Interest:
  • Mammalian and environmental toxicology expertise
  • Regulatory compliance and conformity declarations
  • The production of global product safety documentation
Experience:
  • Chairman of the US Methacrylate Producers Association (MPA), Science Committee and the US Cyanide Council Toxicology Committee, the US Cyanide Counsel
  • Member of the US Acylonitrile Association
  • Sits on several European, US and UK, National regulatory panels and workgroups
  • A member of the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) Scientific Committee
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhDDABT
Current Position Title
Senior Toxicologist
Organizational Affiliation(s)
Gradient Corporation
20 University Rd.
Cambridge, Massachusetts
Areas of Expertise, Discipline, Relevant Experiences
  • Toxicology
  • Exposure assessment
  • Cell and molecular biology
  • Human genetics
  • Environmental toxicology
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhDDABT
Current Position Title
Research Associate
Organizational Affiliation(s)
Global Safety Assessment and Regulatory Affairs

S.C. Johnson & Son, Inc., Racine, WI
Areas of Expertise, Discipline, Relevant Experiences
  • Environmental assessment
  • Environmental fate
  • Ecotoxicology
  • Human and environmental safety assessment of consumer products, including laundry products, insect control products, cleaners, candles, industrial chemicals, radionuclides, insecticides, herbicides, and fungicides, etc.
Recommended by Scientific/Professional
Society or General Public
No

Resources

Guidelines for Peer Review of Toxicological Profiles
Guidelines for peer reviewers of toxicological profiles to enable ATSDR to address your comments.
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for Diisocyanates
Download
Download
The ISI/HISA Dissemination Itself
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Content Source:
Agency for Toxic Substances and Disease Registry