Tetrachloroethylene (PERC)

Toxicological Profile

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of Tetrachloroethylene (PERC).

Details

Title: Toxicological Profile for Tetrachloroethylene (PERC)

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2013

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile was made available for public comment in 2014.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: Six

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY
Areas of Expertise, Discipline, Relevant Experiences
  • Protection of children from immune dysfunction-based chronic diseases
  • Developmental immunotoxicity of environmental chemicals and drugs and the adverse outcomes
  • Patterns of interlinked chronic diseases
  • Immunotoxicity testing to protect against chronic diseases
  • Intervention strategies
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY
Areas of Expertise, Discipline, Relevant Experiences
  • Protection of children from immune dysfunction-based chronic diseases
  • Developmental immunotoxicity of environmental chemicals and drugs and the adverse outcomes
  • Patterns of interlinked chronic diseases
  • Immunotoxicity testing to protect against chronic diseases
  • Intervention strategies
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Research Scientist
Organizational Affiliation(s)
Department of Environmental Sciences & Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill
Areas of Expertise, Discipline, Relevant Experiences
Spatiotemporal variability of tetrachloroethylene in residential indoor air due to vapor intrusion

Environmental epidemiology
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhDMPH
Current Position Title
Scientist
Organizational Affiliation(s)
IARC Monographs Programme
International Agency for Research on Cancer
World Health Organization
Lyon, France
Areas of Expertise, Discipline, Relevant Experiences
Cancer hazard identification
Environmental and occupational cancer hazards
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Scientist Emeritus
Organizational Affiliation(s)
National Cancer Institute
Division of Cancer Epidemiology & Genetics,
Occupational and Environmental Epidemiology Branch
Rockville, Maryland
Areas of Expertise, Discipline, Relevant Experiences
  • Cancer
  • Environmental epidemiology
  • Occupational and environmental causes of cancer
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhDDABT
Current Position Title
Scientist
Organizational Affiliation(s)
Monographs Section
International Agency for Research on Cancer
World Health Organization
Lyon, France
Areas of Expertise, Discipline, Relevant Experiences
  • Cancer
  • Mechanisms of carcinogenicity
  • Risk assessment
  • Cancer prevention
Recommended by Scientific/Professional
Society or General Public
No

Resources

Guidelines for Peer Review of Toxicological Profiles
Guidelines for peer reviewers of toxicological profiles to enable ATSDR to address your comments.
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for Tetrachloroethylene (2014)
Download
Download
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for Tetrachloroethylene (2018)
Download
Download
The ISI/HISA Dissemination Itself
Print
Content Source:
Agency for Toxic Substances and Disease Registry