Methyl tert-Butyl Ether (MTBE)

Toxicological Profile

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of methyl tert-butyl ether (MTBE).

Details

Title: Toxicological Profile for Methyl tert-Butyl Ether (MTBE)

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on these hazardous substances supports public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): August 2020

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public Comment (how and when): ATSDR made a draft of this profile available for public comment in 2020.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, epidemiology, environmental health, and medicine

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
Rutgers University, School of Public Health
Environmental and Population Health Bio-Sciences
Areas of Expertise, Discipline, Relevant Experiences
  • Determination of biomarkers of exposure
  • Measurement of multi-route exposures to volatile organic compounds and disinfection by-products in drinking water
  • Exposure to children.
  • The role of air pollution in exacerbation of asthma
  • Exposures within aircraft and other modes of transportation
  • The sources of pollutants to indoor air and their contribution to personal exposure, and how exposures alter the lung microbiome
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
Environmental Medicine and Pediatrics, University of Rochester Medical Center

School of Medicine and Dentistry, University of Rochester
Areas of Expertise, Discipline, Relevant Experiences
  • Environmental medicine
  • Neurotoxicology
  • Teratology
  • The relationships between brain neurotransmitter systems and children’s neurodevelopment and how such relationships are altered by exposures to environmental toxicants
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Professor Emeritus
Organizational Affiliation(s)
Interdisciplinary Toxicology Program
Pharmaceutical & Biomedical Sciences, College of Pharmacy
University of Georgia
Areas of Expertise, Discipline, Relevant Experiences
  • Toxicology
  • PBPK modeling of VOCs
  • Pesticide toxicology
Recommended by Scientific/Professional
Society or General Public
No

Resources

Additional elements to be added to the public posting as they become available:

Guidelines for Peer Review of Toxicological Profiles
Guidelines for peer reviewers of toxicological profiles to enable ATSDR to address your comments.
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for Methyl tert-Butyl Ether (MTBE)
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The ISI/HISA Dissemination Itself
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Content Source:
Agency for Toxic Substances and Disease Registry