At a glance
Details
Title: Toxicological Profile for Hexachlorobutadiene
Subject of Planned Report: Environmental Protection Agency has determined that hexachlorobutadiene is a possible human carcinogen. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.
Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.
Type of Dissemination: ISI
Timing of Review (including deferrals): July 2018
Type of Review (panel, individual or alternative procedure): Individual
Opportunities for the Public Comment (how and when): A draft was made available for public comment in 2019.
Peer Reviewers Provided with Public Comments before the Review: No
Number of Reviewers: 3
Primary Disciplines or Expertise: toxicology, environmental health, chemistry
Reviewers Selected by (agency or designated outside organization): CDC/ATSDR
Public Nominations Requested for Reviewers: No
Reviewers
Academic and Professional Credentials
PhD
MSc
Current Position Title
Director, UCLA Industrial Hygiene Program
Organizational Affiliation(s)
Department of Environmental Health Sciences, Fielding School of Public Health, UCLA
Areas of Expertise, Discipline, Relevant Experiences
Expertise / Discipline:
- Physical chemistry
- Chemical engineering
- Industrial hygiene
Experience:
- Professor, Step V, Department of Environmental Health Sciences, School of Public Health, UCLA Center for Occupational and Environmental Health, University of California at Los Angeles
- Distinguished Professor, National Taiwan University, School of Public Health, Institute of Environmental Health
- Director, UCLA Industrial Hygiene Program, Department of Environmental Health Sciences, Fielding School of Public Health.
Research areas of interest:
- Detection and quantitative analysis of organic and inorganic pollutants and carcinogens in industrial and agricultural industries, and in the environment at the ng and pg level
- Development of sensitive personal monitoring methods in industry, and workplace protection factors
- Direct reading instruments, and direct-indicating sensors
- Detection and quantitation of toxins in biological tissues which cause cancer or produce unwanted biological effects
- Liquid chromatography-mass spectroscopy
- Gas chromatography-mass spectroscopy; Developmental analytical chemistry dealing with organic, inorganic and organometallic species in-vivo and in-vitro
- Photodecomposition and photosensitization
- Chemiluminescent and bioluminescent analysis
- Multielemental analyses and receptor analyses
- Biological monitoring -screening and specific tests
- Hazardous Waste -field and laboratory methods
- Inductively coupled plasma-mass spectrometry and atomic emission spectroscopy
- Organometallic biological compounds.
Recommended by Scientific/Professional
Society or General Public
Academic and Professional Credentials
Current Position Title
Professor Emeritus of Pharmacology and Toxicology
Organizational Affiliation(s)
College of Pharmacy, University of Georgia
Areas of Expertise, Discipline, Relevant Experiences
Expertise / Discipline:
Pharmacology and toxicology
Experience:
Extensive experience as a peer reviewer for CDC, ATSDR, NIOSH, and EPA.
Research interests:
Questions which impact toxicity risk assessments and experimental research on the use of physiologically-based pharmacokinetic (PBPK) models to predict the administered dose/exposure level anticipated to produce the effect in humans.
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Society or General Public
Academic and Professional Credentials
PhD
MS
Current Position Title
Associate Professor
Organizational Affiliation(s)
Institute of Environmental Engineering, National Sun Yet-sen University
Areas of Expertise, Discipline, Relevant Experiences
Expertise / Discipline:
Civil and environmental engineering
Experience:
- Associate director, Aerosol Science Research Center, National Sun Yat-sen University, Kaohsiung, Taiwan
- Director of Environmental Protection and Safety, Environmental Protection and Safety Center, National Sun Yat-sen University, Kaohsiung, Taiwan, Associate Editor, Journal of Ecology & Natural Resources
- Associate Member (A.M.), American Society of Civil Engineers
- Member, American Chemical Society.
- Engineer-In-Training (EIT)
- Board for Professional Engineers and Land Surveyors, California, Certificate No. EIT 128709
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