2-Hexanone

Toxicological Profile

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of 2-hexanone.

Details

Title: Toxicological Profile for 2-Hexanone

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): September 2016

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public Comment (how and when): A draft will be made available for public comment in 2017.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials
PhD
Current Position Title
Professor of AnesthesiologyDirector of Research
Organizational Affiliation(s)
Albert Einstein College of Medicine
Montefiore Medical Center
Bronx, NY
Areas of Expertise, Discipline, Relevant Experiences
  • Environmental toxicant exposure and endogenous disease processes
  • Role of unsaturated aldehyde electrophiles in Alzheimer’s disease and other neurodegenerative conditions
  • Neurotoxicity and neurodegeneration.
Recommended by Scientific/Professional Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
  • Professor
  • Harold & Muriel Block Chair in Molecular Pharmacology
  • Director, Einstein Center of Toxicology
Organizational Affiliation(s)
Department of Molecular Pharmacology
Albert Einstein College of Medicine
Bronx, NY
Areas of Expertise, Discipline, Relevant Experiences
  • Interaction between genetics and the environment in triggering disease both during central nervous system development and senescence
  • Metal uptake across the blood-brain barrier and distribution in the brain, cellular and molecular mechanisms of neurotoxicity
  • Mechanisms of transport and neurodegeneration in various experimental models
Recommended by Scientific/Professional Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Associate Professor
Organizational Affiliation(s)
Community & Environmental Health
Old Dominion University
Areas of Expertise, Discipline, Relevant
Experiences
  • Industrial hygiene
  • Air pollution
  • Environmental and occupational health and epidemiology
Recommended by Scientific/Professional
Society or General Public
No

Resources

Additional elements to be added to the public posting as they become available:

Guidelines for Peer Review of Toxicological Profiles
Guidelines for peer reviewers of toxicological profiles to enable ATSDR to address your comments.
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for 2-Hexanone
2-Hexanone_Formal_Disposition_to Peer_Review_Comments-508
Download
Download
The ISI/HISA Dissemination Itself
Print
Content Source:
Agency for Toxic Substances and Disease Registry