1,2-Diphenylhydrazine

Toxicological Profile

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of 1,2-Diphenylhydrazine.

Details

Title: Toxicological Profile for 1,2-Diphenylhydrazine

Subject of Planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): May 2018

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public Comment (how and when): A draft of this profile was made available for public comment June 2019.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
Laboratório de Ecotoxicologia e Genotoxicidade LAEG
Faculdade de Tecnologia UNICAMP, Brazil
Areas of Expertise, Discipline, Relevant Experiences
Expertise / Discipline:
  • Environmental and regulatory toxicology
  • Mutagenesis
  • Ecotoxicology
  • Toxicology of dyes and pesticides in water

Experience:
Dr. Umbuzeiro graduated in Biology in the State University of Campinas- UNICAMP (1979), master’s and in Genetics and Molecular Biology from UNICAMP (1985) and Ph.D. in Genetics and Molecular Biology from UNICAMP (1990). She has been a visiting Professor at NIEHS and USEPA and a full professor at State University of Campinas – Faculty of Technology -UNICAMP.
She worked for 22 years for the Environmental Protection Agency of the São Paulo State of Brazil (CETESB). There, she was president of the Mutagen Society Member of the Editorial Board of Environmental Molecular Mutagenesis journal. Dr. Umbuzeiro is an expert and a member of the UNESCO-International Initiative on water quality Experts Advisory Group.
Recommended by Scientific/Professional Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Toxicologist
Organizational Affiliation(s)
General Toxicology and Cancer GroupNIH
Areas of Expertise, Discipline, Relevant Experiences
Expertise / Discipline:
  • Toxicology
  • Molecular biology
  • Mixtures
Experience:
Dr Rider designs and evaluates results from toxicological studies of chemicals selected for investigation by the NTP. She is particularly interested in developing methods for assessing mixture toxicity based on data from individual chemicals.
Dr. Rider received her B.S. from Tulane University, New Orleans, LA in Environmental Studies and Biology and her Ph.D. from North Carolina State University, Raleigh, NC in Environmental Toxicology. She completed post-doctoral training in the Reproductive Toxicology Branch of the National Health and Environmental Effects Research Laboratory, U. S. Environmental Protection Agency and the Nicholas School of the Environment at Duke University.
Recommended by Scientific/Professional Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Associate Professor of Chemistry
Organizational Affiliation(s)
Department of Chemistry,
University of Pennsylvania
Areas of Expertise, Discipline, Relevant Experiences
Expertise / Discipline:
  • Inorganic and materials chemistry
  • Molecular complexes
  • Inert atmosphere/Schlenk line synthesis of inorganic and organometallic complexes
  • Use of x-ray crystallography, NMR, FTIR, and UV-Visible absorption spectroscopies, electrochemistry and magnetic susceptibility studies
  • Chemistries and electronic structure effects of the lanthanides, uranium and main group elements
Experience:
Dr. Schelter received his B.S. degree from Michigan Technological University (1999), Ph.D. from Texas A&M University, followed by postdoctoral fellowships at Los Alamos National Laboratory. In 2009, he became Assistant Professor of Chemistry at the University of Pennsylvania, and Associate Professor of Chemistry in 2015. He received the ACS Harry Gray Award for Creative Work in Inorganic Chemistry by a Young Investigator (2016). He is on the:

  • Editorial Advisory Board Member of Inorganic Chemistry (2016-2018)
  • ACS Division of Inorganic Chemistry, Chair Elect (2016)
  • Fellow of the Royal Society of Chemistry (2017)
  • U.S. Environmental Protection Agency Green Chemistry Challenge Award Recipient (2017)
Recommended by Scientific/Professional Society or General Public
No

Resources

Peer Review Charge for 1,2-Diphenylhydrazine
Review the peer review charge and post-public draft of 1,2-Diphenylhydrazine.
CDC/ATSDR’s Response to Reviewers’ Comments for Toxicological Profile for 1,2-Diphenylhydrazine
Download
Download
The ISI/HISA Dissemination Itself
Print
Content Source:
Agency for Toxic Substances and Disease Registry