Interaction Profile on Metallic Ions in Fracturing Waste

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR report shares the interaction profile on metallic ions in fracturing waste.

Details

Title: Interaction Profile on Metallic Ions In Fracturing Waste

Subject of planned Report: The ATSDR interaction profile succinctly characterizes the toxicologic and adverse health effects for the substances being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): July 2017

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile will be made available for public comment in 2018.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
The George Perkins Marsh Institute
Center for Toxicology, Environment, and Development
Clark University, Worcester, MA
Areas of Expertise, Discipline, Relevant Experiences
  • Use of various biomarkers and physiologically-based pharmacokinetic models to improve risk assessment for carcinogens
  • Quantitative treatment of inter-individual variability in susceptibility for a wide variety of non-cancer effects
  • Use of Monte Carlo simulations to represent the combined effects of multiple sources of uncertainty and variability
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Professor
Organizational Affiliation(s)
Department of Population Health and Reproduction,
School of Veterinary Medicine
Department of Obstetrics and Gynecology, School of Medicine
Center for Health and the Environment, University of California, Davis, CA

Areas of Expertise, Discipline, Relevant Experiences
  • Ovarian function
  • Early pregnancy and comparative reproductive endocrinology
  • Wildlife reproduction
  • Comparative reproductive endocrinology
  • Toxicology
  • Epidemiology
  • Reproduction of non-domestic species
  • Endocrine aspect of female fertility and early pregnancy
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhDMHS
Current Position Title
Assistant Professor of Epidemiology (Environmental Health)
Organizational Affiliation(s)
School of Public Health: Climate Change and Health; Deziel Lab, Environmental Health Sciences
Yale Cancer Center: Cancer Prevention and Control
Yale University, New Haven, CT 06520
Areas of Expertise, Discipline, Relevant Experiences
Expertise:
Dr. Deziel's expertise includes interface between exposure to environmental agents and human disease, including women’s health and children’s health outcomes. He also has expertise in pesticides, persistent organic pollutants, and polycyclic aromatic hydrocarbons.

Research focus:
Evaluating, improving, and developing exposure estimates for application in environmental epidemiologic studies

Experience:
Dr. Deziel has experience in critical methodologic issues, such as the relative contribution of different routes of exposure, between- and within-participant variability in exposure measurements over time, and surrogate exposure measures. additionally, he has investigated how environmental exposures are changing with new techniques for energy production (e.g., hydraulic fracturing) and climate change.
Recommended by Scientific/Professional
Society or General Public
No

Academic and Professional Credentials
PhD
Current Position Title
Professor and Chair, Department of Environmental Medicine
Professor, Department of Biochemistry and Molecular Pharmacology
Organizational Affiliation(s)
Department of Environmental Medicine
New York University Medical Center
Nelson Institute of Environmental Medicine
Tuxedo, New York
Areas of Expertise, Discipline, Relevant Experiences
Expertise:
  • Molecular mechanisms of metal carcinogenesis
  • Epigenetics
  • Regulation of transcription
  • Chromatin structure and dynamics
  • Pharmacology
Experience:
Dr. Costa has over 300 publications and is a recipient of Lifetime Achievement award from the Metals Specialty Section of the Society of Toxicology.
Recommended by Scientific/Professional
Society or General Public
No

Resources

Additional elements to be added to the public posting as they become available:

Guidelines for Peer Review of Toxicological Profiles
Guidelines for peer reviewers of toxicological profiles to enable ATSDR to address your comments.
The ISI/HISA Dissemination
Print
Content Source:
Agency for Toxic Substances and Disease Registry