At a glance
NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR report shares the assessment of the evidence for the drinking water contaminants at Camp LeJeune.
Details
Title: ATSDR Assessment of the Evidence for the Drinking Water Contaminants at Camp Lejeune and Specific Cancers and Other Diseases.
Subject of Planned Report: The ATSDR Report reviews the evidence for adverse health effects from drinking water contaminants at Camp Lejeune.
Purpose of Planned Report: The purpose of the assessment is to evaluate the strength of the evidence supporting causality of adverse health effects from exposures to contaminants. This includes trichloroethylene (TCE), tetrachloroethylene (PCE), and other contaminants that were present in the drinking water at U.S. Marine Corps Base Camp Lejeune from the 1950s through 1985.
Type of Dissemination: ISI
Timing of Review (including deferrals): August 2016
Type of Review (panel, individual or alternative procedure): Individual
Opportunities for the Public to Comment (how and when): No
Peer Reviewers Provided with Public Comments before the Review: No
Anticipated Number of Reviewers: Four
Primary Disciplines or Expertise: toxicology, environmental health, cancer epidemiology
Reviewers Selected by (agency or designated outside organization): CDC/ ATSDR
Public Nominations Requested for Reviewers: No
Reviewers
- The relationship between drinking water contaminants and abnormal pregnancy outcomes
- Neurological disorders and cancer
- Impact of lead hazard reduction measures among inner-city children
- Birth defects and stillbirths following prenatal exposure to tetrachloroethylene-contaminated drinking water
Society or General Public
- Quantitative risk assessment process for cancer risk modeling
- Cancer risk assessments for over 20 chemicals, including dioxin, asbestos, methylene chloride, nickel and nickel compounds
- 1,3-butadiene
- Vinyl and vinylidene chloride
- Ethylene oxide
- Cadmium
Society or General Public
- The health effects of occupational and environmental toxins such as pesticides
- Ionizing radiation
- Air pollution on chronic diseases including neurodegenerative disorders (Parkinson’s disease)
- Cancers
- Adverse birth outcomes
- Asthma
Society or General Public
- NIH Director’s Award
- PHS Special Recognition Award
- NIH Merit Award
- John Goldsmith Award for Outstanding Contributions to Environmental Epidemiology from the International Society for Environmental Epidemiology
- NIH Director’s Award for the Deepwater Horizon Gulf Oil Spill Study
- Evaluating cancer and other disease risks associated with agricultural exposures
- Chemicals in the workplace and the general environment
- Physical activity and disease
- Methodologic issues in occupational epidemiology
- Studies of under-investigated populations
Society or General Public
Charge to peer reviewers
- Are the individual disease tables sufficiently comprehensive to make our case or did we omit an important epidemiological study that should be included in the tables?
- Are we interpreting the epidemiological evidence and available toxicological information for each exposure-disease relationship appropriately? Particular emphasis on the mechanistic information provided for PCE and bladder cancer.
- For each exposure-disease relationship covered in our assessment, is the summary of the evidence and concluding classification sufficiently supported by the information provided in the disease table and the discussion that follows the table, or do we need to include additional information (e.g., findings from animal studies), to support our conclusion?
- Do you have any suggestions on how to strengthen our assessment of the evidence for any of the diseases evaluated (e.g., is their toxicological information that could be added to strengthen the assessment?)